1,265 research outputs found

    Study of the Problems of Persons with Disability (PWD) Using FRMs

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    In this paper authors find the interrelations and the hidden pattern of the problems faced by the PWDs and their caretakers using Fuzzy Relational Maps (FRMs). Here they have taken the problems faced by the rural persons with disabilities in Melmalayanur and Kurinjipadi Blocks, Tamil Nadu, India

    Fuzzy Analysis of School Dropouts and their Life After

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    In this book authors study and analyze the problem of school dropouts and their life after. The problems can by no means be analyzed by collecting the numerical data. For such data can only serve as information beyond that the data can be of no use, for the school dropouts suffer an environment change after becoming a school dropout. Thus the emotions of the school dropout; is technically involved. A school dropout can be a child labourer, a rag picker or a social miscreant or be in police custody or be in a rehabilitation home if he/she is a runaway. The story is entirely different if the child is a school dropout due to abduction. In the case of female children the problem is more serious for they are sexually exploited and in most cases they land up in brothels as prostitutes. Thus their life after is a complete misery for these children not only have been denied the right to enjoy their childhood but from a very young age they are sexually exploited and invariably the majority of them become victims of sexually transmitted disease or suffer from cervical cancer or suffer from AIDS/HIV with no one to take care of them. Majority of these children die as orphans. Who is responsible for all these? Who is going to take up their issue? The question has no answer and the life after for these female children is a misery. The school dropout of female children due to child marriage is entirely another issue, for in most cases they are married to men four times their age. They suffer a very different type of orthodoxy associated with Indian culture and heritage. All this is seconded by Laws of Manu for a women is only an object so without any objection they can do anything to it. That is why the popular daily, The Times of India reports “27% spike in procurement of minor girls”. So they have once again justified women are just objects sold or thrown away for their convenience. This book does not study the female dropout and their life after

    Super Fuzzy Matrices and Super Fuzzy Models for Social Scientists

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    This book introduces the concept of fuzzy super matrices and operations on them. This book will be highly useful to social scientists who wish to work with multi-expert models. Super fuzzy models using Fuzzy Cognitive Maps, Fuzzy Relational Maps, Bidirectional Associative Memories and Fuzzy Associative Memories are defined here. The authors introduce 13 multi-expert models using the notion of fuzzy supermatrices. These models are described with illustrative examples. This book has three chapters. In the first chaper, the basic concepts about super matrices and fuzzy super matrices are recalled. Chapter two introduces the notion of fuzzy super matrices adn their properties. The final chapter introduces many super fuzzy multi expert models.Comment: 280 page

    RESERVATION FOR OTHER BACKWARD CLASSES IN INDIAN CENTRAL GOVERNMENT INSTITUTIONS LIKE IITs, IIMs AND AIIMS – A STUDY OF THE ROLE OF MEDIA USING FUZZY SUPER FRM MODELS

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    The new notions of super column FRM model, super row FRM model and mixed super FRM model are introduced in this book. These three models are introduced specially to analyze the biased role of the print media on 27 percent reservation for the Other Backward Classes (OBCs) in educational institutions run by the Indian Central Government. This book has four chapters. In chapter one the authors introduce the three types of super FRM models. Chapter two uses these three new super fuzzy models to study the role of media which feverishly argued against 27 percent reservation for OBCs in Central Government-run institutions in India. The experts we consulted were divided into 19 groups depending on their profession. These groups of experts gave their opinion and comments on the news-items that appeared about reservations in dailies and weekly magazines, and the gist of these lengthy discussions form the third chapter of this book. The fourth chapter gives the conclusions based on our study. Our study was conducted from April 2006 to March 2007, at which point of time the Supreme Court of India stayed the 27 percent reservation for OBCs in the IITs, IIMs and AIIMS. After the aforesaid injunction from the Supreme Court, the experts did not wish to give their opinion since the matter was sub-judice. The authors deeply acknowledge the service of each and every expert who contributed their opinion and thus made this book a possibility. We have analyzed the data using the opinion of the experts who formed a heterogeneous group consisting of administrators, lawyers, OBC/SC/ST students, upper caste students and Brahmin students, educationalists, university vice-chancellors, directors, professors, teachers, retired Judges, principals of colleges, parents, journalists, members of the public, politicians, doctors, engineers, NGOs and government staff

    Fuzzy and Neutrosophic Analysis of Periyar's views on Untouchability

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    This book is organized into four chapters. In Chapter One we just introduce the basic Fuzzy and Neutrosophic tools used in the analysis of the social evil of Untouchability. Since the notion of caste is based on themind, it is appropriate to use Fuzzy and Neutrosophic theory. In Chapter Two we use the opinion of several experts to analyze the various aspects of untouchability. Here, we use the tools that have been described in Chapter One. Fuzzy Directed Graphs and Neutrosophic Directed Graphs of these Fuzzy and Neutrosophic models happen to be very dense. We have represented 16 such graphs in this book. In Chapter Three we give a brief introduction about the life and struggle of Periyar. The fourth and concluding chapter gives observations drawn from our mathematical results based on the Fuzzy and Neutrosophic analysis.Comment: 385 pages, 16 figure

    Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis

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    Viruses are one of the major causes of acute and chronic infectious diseases and thus a major contributor to the global burden of disease. Several studies have shown how viruses have evolved to hijack basic cellular pathways and evade innate immune response by modulating key host factors and signaling pathways. A collective view of these multiple studies could advance our understanding of virus-host interactions and provide new therapeutic perspectives for the treatment of viral diseases. Here, we performed an integrative meta-analysis to elucidate the 17 different host-virus interactomes. Network and bioinformatics analyses showed how viruses with small genomes efficiently achieve the maximal effect by targeting multifunctional and highly connected host proteins with a high occurrence of disordered regions. We also identified the core cellular process subnetworks that are targeted by all the viruses. Integration with functional RNA interference (RNAi) datasets showed that a large proportion of the targets are required for viral replication. Furthermore, we performed an interactome-informed drug re-purposing screen and identified novel activities for broad-spectrum antiviral agents against hepatitis C virus and human metapneumovirus. Altogether, these orthogonal datasets could serve as a platform for hypothesis generation and follow-up studies to broaden our understanding of the viral evasion landscape

    Cation and anion transport through hydrophilic pores in lipid bilayers

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    To understand the origin of transmembrane potentials, formation of transient pores, and the movement of anions and cations across lipid membranes, we have performed systematic atomistic molecular dynamics simulations of palmitoyl-oleoyl-phosphatidylcholine (POPC) lipids. A double bilayer setup was employed and different transmembrane potentials were generated by varying the anion (Cl−)(Cl−) and cation (Na+)(Na+) concentrations in the two water compartments. A transmembrane potential of ∼ 350 mV∼350mV was thereby generated per bilayer for a unit charge imbalance. For transmembrane potential differences of up to ∼ 1.4 V∼1.4V, the bilayers were stable, over the time scale of the simulations (10–50 ns)(10–50ns). At larger imposed potential differences, one of the two bilayers breaks down through formation of a water pore, leading to both anion and cation translocations through the pore. The anions typically have a short residence time inside the pore, while the cations show a wider range of residence times depending on whether they bind to a lipid molecule or not. Over the time scale of the simulations, we do not observe the discharge of the entire potential difference, nor do we observe pore closing, although we observe that the size of the pore decreases as more ions translocate. We also observed a rare lipid flip-flop, in which a lipid molecule translocated from one bilayer leaflet to the opposite leaflet, assisted by the water pore.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87872/2/074901_1.pd
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